NFL · November 23, 2025

Jacksonville Jaguars @ Arizona Cardinals

Free LineCrush game report for Jacksonville Jaguars @ Arizona Cardinals on November 23, 2025, with matchup analysis and pick ideas generated for the daily slate. Reports can update as lineups, injuries, and odds develop, so confirm time-sensitive details before acting.

Matchup Analysis

Jacksonville's Offensive Line Crisis

The Jaguars' offensive line is severely depleted with Robert Hainsey (hamstring) ruled OUT, Wyatt Milum (knee) ruled OUT, and Anton Harrison (hamstring) inactive. Ezra Cleveland is also questionable with a knee sprain, forcing Jacksonville to piece together protection for Trevor Lawrence against Arizona's pass rush.

Brian Thomas Jr. Absence Impact on Receiving Attack

Wide receiver Brian Thomas Jr. will miss his third consecutive game due to an ankle sprain. However, Trevor Lawrence has developed strong chemistry with alternative receivers Jakobi Meyers and Parker Washington, which should provide some offensive continuity despite losing the team's top target.

Jaguars' Pass Rush Adjustments Without Travon Walker

Defensive end Travon Walker is inactive due to a knee injury suffered against the Chargers. Jacksonville will need contributions from reserve defensive linemen Dawuane Smoot, Danny Striggow, and B.J. Green II, with linebacker Dennis Gardeck potentially seeing increased defensive snaps.

Secondary Concerns for Jacksonville

Cornerback Jourdan Lewis remains inactive after missing the previous two games with a neck injury, while fellow cornerback Jarrian Jones is dealing with a quadricep injury. These absences could create coverage vulnerabilities against Arizona's receiving options.

Arizona's Quarterback Depth Test

The Cardinals are without starting quarterback Kyler Murray, who is on injured reserve with a foot injury and will miss an extended period. Arizona's backup quarterback will face a Jaguars defense seeking to exploit the transition at quarterback.

Pick Ideas

Jaguars Team Total Under

Jacksonville's decimated offensive line and missing skill position players should limit offensive output. Consider betting the Jaguars team total under 23.5.

Game Total Under Play

Both teams are hampered by offensive injuries and backups under center, suggesting a lower-scoring defensive battle. The 47.5 total appears inflated given the circumstances.

Defensive Scoring Props

With Jacksonville missing edge rusher Travon Walker and Arizona lacking starting QB Kyler Murray, expect increased pressure and turnover opportunities favoring defensive contributors on both sides.